Detalhe da pesquisa
1.
Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation.
Mol Cell
; 82(11): 1992-2005.e9, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417664
2.
Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity.
Nature
; 623(7989): 1034-1043, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993715
3.
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Mol Cell
; 81(18): 3833-3847.e11, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34289383
4.
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors.
Bioorg Med Chem Lett
; 30(9): 127061, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32173197
5.
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening.
Bioorg Med Chem Lett
; 29(4): 638-645, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626558
6.
Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays.
Bioorg Med Chem Lett
; 27(2): 342-346, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899265
7.
Enhanced room-temperature ferromagnetism on (In0.98-xCoxSn0.02)2O3 films: magnetic mechanism, optical and transport properties.
Phys Chem Chem Phys
; 19(43): 29472-29482, 2017 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29082400
8.
NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma Tumor Growth.
Mol Cancer Res
; 22(4): 386-401, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294692
9.
Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.
Cell Chem Biol
; 29(7): 1200-1208.e6, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35429459
10.
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.
J Med Chem
; 63(3): 1337-1360, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31910017
11.
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion.
Adv Sci (Weinh)
; 7(14): 2000098, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32714746
12.
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors.
Eur J Med Chem
; 163: 281-294, 2019 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529546
13.
Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening.
RSC Adv
; 9(9): 4917-4924, 2019 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35514635
14.
Computer-Aided Drug Design in Epigenetics.
Front Chem
; 6: 57, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29594101
15.
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening.
Eur J Med Chem
; 157: 867-876, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30145373
16.
Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1.
ACS Chem Biol
; 13(3): 772-781, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381856